Eur J Endocrinol 2006; 154: 899–906 21 Malkin CJ, et al The ef

Eur J Endocrinol 2006; 154: 899–906. 21. Malkin CJ, et al. The effect of testosterone replacement on endogenous inflammatory

cytokines and lipid profiles in hypogonadal men. J Clin Endocrinol Metab 2004; 89: 3313–8. 22. Bhasin S, et al. Testosterone therapy in adult men with androgen deficiency syndrome: An endocrine society clinical practice guideline. J Clin End Metab 2010; 91: 1995–2010. 23. Basaria S, et al. Adverse events associated with testosterone administration. N Eng J Med 2010; 363: 109–22. 24. Srinivas-Shankar U, et al. Effect of testosterone on muscle strength, physical function, ERK high throughput screening body composition, and quality of life in frail elderly men: a randomised, double-blind, placebo controlled study. J Clin End Metab 2010; 95: 639–50. 25. Jones TH. ‘What should I do with a 60-year old man with a slightly low serum total testosterone concentration and normal levels of serum gonadotrophins?’ Clin Endocrinol 2010; 72: 584–8. Dr Richard Quinton1 and Dr Arif Ullah21Consultant Endocrinologist, Royal Victoria Infirmary, and Senior Lecturer, Institute of Human Genetics, University of Newcastle-upon-Tyne, UK 2Specialist Trainee Registrar, Endocrinology and Diabetes, Royal Victoria Infirmary, Newcastle-upon-Tyne, UK 1. Harman

SM, et al. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. J Clin Endocrinol Metab 2001; 86: 724–31. 2. Bhasin S, et click here al. Testosterone therapy in adult men with androgen deficiency syndromes: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 2006; 91: 1995–2010. 3. Turner HE, Wass JA. Gonadal function in men with chronic illness, Clin Endocrinol (Oxf) 1997; 47(4): 379–403. 4. Tajar A, et al. Characteristics of secondary, primary, and compensated hypogonadism in aging men: Evidence from the European Male Ageing Study. J Clin Endocrinol Metab 2010; 95: 1810–18. 5. Wu FC, et al., the European Male Aging Study Group. Hypothalamic-pituitary-testicular

axis disruptions tuclazepam in older men are differentially linked to age and modifiable risk factors: the European Male Aging Study. J Clin Endocrinol Metab 2008; 93: 2737–45. 6. Prelevic GM, Jacobs HS. Menopause and post-menopause. Baillière’s Clin Endocrinol Metab 1997; 11: 311–40. 7. Stampfer MJ, Colditz GA. Estrogen replacement therapy and coronary heart disease: a quantitative assessment of the epidemiologic evidence. Prev Med 1991; 20(1): 47–63. 8. Barrett-Connor E, Laakso M. Ischemic heart disease risk in postmenopausal women. Effects of estrogen use on glucose and insulin levels. Arterioscler Thromb Vasc Biol 1990; 10: 531–4. 9. Stampfer MJ, et al. Menopause and heart disease: a review. Ann N Y Acad Sci 1990; 592: 193–203. 10. Barrett-Connor E, Bush TL. Estrogen and coronary disease. JAMA 1991; 265: 1861–7. 11. Henderson BE, et al. Decreased mortality in users of estrogen replacement therapy. Arch Intern Med 1991; 151: 75–8. 12. Paganini-Hill A, et al.

Comments are closed.