PubMedCentralPubMedCrossRef 6. Holcomb JB, Minei KM, Scerbo ML, Radwan ZA, Wade CE, Kozar RA, Gill BS, Albarado R, McNutt MK, Khan S, Adams PR, McCarthy JJ, Cotton BA: Admission rapid thrombelastography can replace conventional coagulation tests in the emergency department: experience with 1974 consecutive trauma patients. Ann Surg 2012, 256:476–486.PubMedCrossRef

7. Tauber H, Innerhofer P, Breitkopf R, Westermann I, Beer R, El Attal R, Strasak A, Mittermayr M: Prevalence and impact of abnormal ROTEM(R) assays in severe blunt trauma: results of the ‘Diagnosis and Treatment of Trauma-Induced Coagulopathy (DIA-TRE-TIC) study’. Br J Anaesth 2011, 107:378–387.PubMedCrossRef SCH727965 8. Johansson PI: Goal-directed hemostatic resuscitation Nepicastat cell line for massively bleeding patients: the Copenhagen concept. Transfus Apher Sci 2010, 43:401–405.PubMedCrossRef 9. Wang SC, Shieh JF, Chang KY, Chu YC, Liu CS, Loong CC, Chan KH, Mandell S, Tsou MY: Thromboelastography-guided transfusion decreases intraoperative blood transfusion during orthotopic liver transplantation: randomized clinical trial. Transplant Proc 2010, 42:2590–2593.PubMedCrossRef 10. Schochl H, Nienaber U, Hofer G, Voelckel W, Jambor C, Scharbert G, Kozek-Langenecker S, Solomon C: Goal-directed coagulation management of major trauma patients using thromboelastometry (ROTEM)-guided administration

of fibrinogen concentrate and prothrombin complex concentrate. Crit Care 2010, 14:R55.PubMedCentralPubMedCrossRef 11. Shore-Lesserson L, Manspeizer HE, DePerio M, Francis S, Vela-Cantos F, Ergin MA: Thromboelastography-guided transfusion algorithm reduces transfusions in complex cardiac surgery. Anesth

Analg 1999, 88:312–319.PubMed 12. Johansson PI, Stensballe J: Effect of haemostatic control resuscitation on mortality in massively bleeding patients: a before and after study. Vox Sang 2009, 96:111–118.PubMedCentralPubMedCrossRef 13. Kashuk JL, Moore EE, Wohlauer M, Johnson JL, Pezold M, Lawrence J, Biffl WL, Burlew CC, Barnett C, Sawyer M, Sauaia A: Initial experiences with point-of-care rapid thrombelastography for management of life-threatening postinjury coagulopathy. Transfusion 2012, 52:23–33.PubMedCrossRef 14. mafosfamide Yao D, Li Y, Wang J, Yu W, Li N, Li J: Effects of recombinant activated factor VIIa on abdominal trauma patients. Blood Coagul Fibrinolysis 2014, 25:33–38.PubMedCrossRef 15. Stassen NA, Bhullar I, Cheng JD, Crandall M, Friese R, Guillamondegui O, Jawa R, Maung A, Rohs TJ Jr, Sangosanya A, Schuster K, Seamon M, Tchorz KM, Zarzuar BL, Kerwin A, Eastern see more Association for the Surgery of Trauma: Nonoperative management of blunt hepatic injury: an Eastern Association for the Surgery of Trauma practice management guideline. J Trauma Acute Care Surg 2012, 73:S288-S293.PubMedCrossRef 16. Frith D, Brohi K: The pathophysiology of trauma-induced coagulopathy. Curr Opin Crit Care 2012, 18:631–636.PubMedCrossRef 17.