05, 95% CI: 0.94 to 1.17; P=0.409). Table 2 Univariate demographic analysis of stroke mortality in P505-15 mouse Southern Iran Figure 1 Stratified analysis of age and sex associated with hospital mortality in patients with all types of stroke in Southern Iran Table 3 Covariates associated with hospital mortality based on multiple logistic regression analysis Trends of Mortality Over Time During the study period, the percentage of all types of stroke admissions Inhibitors,research,lifescience,medical to Nemazee Hospital decreased from 5% (95% CI: 4.9% to 5.1%) in 2001 to 4.5% (95% CI: 4.4% to 4.6%) in 2010 (P<0.001). However, the mortality rate among the hospitalized stroke patients (figure 2)
increased from 17.7% (95% CI: 16.7% to 18.7%) to 22.2% (95% CI: 21.6% to 23.4%) (P<0.001). This observation was made in both genders. Figure 2 Trend of overall Inhibitors,research,lifescience,medical mortality associated with all types of stroke in southern Iran between 2001 and 2010 Discussion Four important observations can be made from this analysis. First is the higher in-hospital mortality (20%) in comparison to developed countries.1 Our result chimes in with the reported case fatality rate from any stroke in central Iran
(24.6%).6 Furthermore, mortality rates in central and southern Iran are higher than those reported from the nearby states. Thirty-day case fatality rate for stroke in Arab Inhibitors,research,lifescience,medical middle-eastern and North African countries, where socioeconomic characteristics of the population are generally similar to Iran, falls between 10% and 17.3%.11 Several factors may have contributed to these results, including absence of health institution infrastructure such as specialized stroke units and underutilization of thrombolysis, both of which are known to positively Inhibitors,research,lifescience,medical influence outcomes in acute ischemic stroke.12 Moreover, stroke Inhibitors,research,lifescience,medical awareness is lacking among most of the Iranian general population.13
This can lead to the referral of stroke patients in late stages and increased mortality. Post-stroke care has been another issue which may have influenced outcome. Surveys of Iranian stroke survivors suggested Parvulin that the social, financial, and rehabilitative support for stroke was inadequate.14 Unlike developed countries, nursing facilities are not available in Iran; consequently, most stroke survivors are discharged home.6 The lack of organized rehabilitation care and the nonsystematic nature of family care can lead to lengthy recovery, probable readmissions, and perhaps higher mortality.15 The second observation from this analysis is noted differences in epidemiological characteristics of the stroke population in Iran. Our results suggest that a higher proportion of stroke occurs in young adults and children (14% of all stroke cases occurred in those younger than 45). These rates are comparable to those reported in the nearby countries such as Qatar (18%) and Libya (19.