Anti-ulcer activity was evaluated by measuring the ulcer index (UI) and ulcer inhibition. The UI was significantly reduced in all treated animals. A dramatic decrease in the UI was observed following the administration of total extract (100 mg/kg, p < 0.001) and CHCl3 fraction (42 mg/kg, ***p < 0.001) in comparison with the control group. The percentage ulcer inhibition with total extract at a dose of 100 mg/kg (97.66%) and CHCl3 fraction at a dose of 42 mg/kg (96.96%) was found to be higher (p < 0.001) than the reference group (cimetidine 100 mg/kg) (87.08%).

The pharmacological and histological results of the present study proved that the aerial PCI-32765 inhibitor flowering parts of CBB possess preventive activity against peptic ulcer, supporting

the traditional assertion in southern Iranian folk medicine.”
“The optical-absorption edge of single crystals of CaWO4, SrWO4, BaWO4, and PbWO4 has been measured under high pressure up to similar to 20 GPa at room temperature. From these measurements, we have obtained the evolution of the band-gap energy with pressure. We found a low-pressure range (up to 7-10 GPa) where alkaline-earth tungstates present a very small E-g pressure dependence (-2.1 < dE(g)/dP < 8.9 meV/GPa). In contrast, in the same pressure range, PbWO4 has a pressure coefficient of -62 meV/GPa. The high-pressure range is characterized in the four compounds by an abrupt decrease of Eg followed buy GDC 0032 by changes in dE(g)/dP. The band-gap collapse is larger than 1.2 eV in BaWO4. We also calculated the electronic-band structures and their pressure evolution. The calculations allow us to interpret experiments considering the different electronic configurations of divalent metals. Changes in the pressure evolution of E-g are correlated with the occurrence of pressure-induced phase transitions. The band structures

for the low-and high-pressure phases are also reported. No metallization of any of the compounds is detected in experiments nor is it predicted by the calculations. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3622322]“
“Purpose: This Study Sought to identify sociodemographic, psychosocial, and clinical factors associated with increased postsurgery depressive symptoms among inner-city minority patients MLN4924 research buy recovering from a mandibular fracture.

Patients and Methods: Surveys of African American and Hispanic adults receiving treatment at King/Drew Medical Center for a mandible fracture (n = 98) are used to identify factors associated with increased postsurgery depressive symptoms. Using correlation coefficients and t tests, bivariate relationships between patient characteristics and depressive symptoms at first follow-up were examined. Multiple regression analysis was used, predicting depressive symptoms at 1 month postadmission by entering covariates that were found to be significant at the bivariate level.