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“Health effects attributable to air pollution exposure in Chinese population have been least understood. The authors conducted a meta-analysis on 33 time-series and case-crossover studies conducted in China to assess mortality effects of short-term exposure to particulate matter with aerodynamic diameters less than 10 and 2.5 mu m (PM10 and PM2.5), sulfur dioxide (SO2), nitrogen dioxide (NO2), ozone (O-3) and carbon monoxide (CO). Significant associations between
air pollution exposure and increased mortality risks were observed in the pooled estimates for all pollutants of interest. In specific, each 10 mu g/m(3) increase in PM2.5 was askwiated with a 0.38% (95% Confidence Interval, CI: 0.31, 0.45) increase in total mortality, a 0.51% (95% CI: 0.30, 0.73) in respiratory mortality, GNS-1480 mouse and a 0.44% (95% CI: 033, 0.54) in cardiovascular selleck chemicals llc mortality. When current annual PM2.5 levels in mega-Chinese cities to be reduced to the WHO Air Quality Guideline (AQG)
of 10 mu g/m(3), mortality attributable to short-term exposure to PM2.5 could be reduced by 2.7%, 1.7%, 2.3%, and 62% in Beijing, Shanghai, Guangzhou and Xi’an, respectively. The authors recommend future studies on the nature of air pollution concentration and health effect relationships in Chinese population to support setting stringent air quality standards to improve public health.
(C) 2013 Elsevier Ltd. All rights reserved.”
“Systemic lupus erythematosus (SLE) is an auto-immune disease that is characterised by autoantibody production. Male lupus is rare, apart from at either end of the age spectrum.
In this series, we review the histories of six male lupus patients attending our service.
Our patients presented in middle age and tended to develop haematological abnormalities, renal involvement and neurological manifestations which preceded the onset of their skin and joint complaints. Our patients accrued damage rapidly and overall did badly. They tended to respond sub-optimally to standard treatments. These cases highlight the need an increased awareness that male SLE patients present with a wide variety of symptoms, and that they accrue Selleckchem Nepicastat damage quickly. There is a need for timely diagnosis and appropriate initiation of treatment. This may help avoid preventable organ damage and increase the survival of men with SLE.”
“We present a detailed study of the luminescence at 3.42 eV usually observed in a-plane epitaxial lateral overgrowth (ELO) GaN grown by hydride vapor phase epitaxy on r-plane sapphire. This band is related to radiative recombination of excitons in a commonly encountered extended defect of a-plane GaN: I(1) basal stacking fault.