In general, parents tend to estimate the dental fear of their children slightly higher than their children. “
“International Journal of Paediatric Dentistry 2010; 20: 305–312 BAY 80-6946 cell line Background.  Kallmann syndrome (KS) is a rare genetic disorder characterised

by central hypogonadism with a lack of sense of smell and in some cases renal aplasia, deafness, syndactyly, cleft lip/palate, and dental agenesis. To date, five genes for KS have been identified: KAL1, located on the X chromosome, and FGFR1, PROKR2, PROK2 and FGF8, which are involved in autosomally transmitted forms of KS. Aim.  The study characterised the dental ageneses of individuals with KS associated with mutations in the FGFR1 gene. Design.  Six individuals displaying dental agenesis were included. Clinical and radiological dental evaluations as well as

medical anamneses were carried out. Results.  Microdontia, screwdriver-shaped mandibular incisors, thin molar roots, and patterns of dental agenesis in both dentitions were observed. One to nine teeth were missing, most frequently, in descending order, lateral mandibular incisors, second premolars of upper and lower jaws, and lateral maxillary incisors. The pattern of dental agenesis is associated with four new mutations in the FGFR1 gene. Conclusion: Dental agenesis may be a clinical feature of Kallmann syndrome caused by a mutation in the FGFR1 gene. These findings highlight the role that odontologists selleck can play in the early diagnosis and treatment of gonadotropic deficiency. “
“Knowledge of the genetic and environmental influences in caries aetiology has relevance for preventive Sodium butyrate dentistry. This classical twin study compared concordance of mutans streptococci (MS) and lactobacilli (LB) colonization, enamel defects, and caries in a cohort

of 4–6-year-old mono- (MZ) and dizygotic (DZ) twin pairs. The twins were examined for prevalence and concordance of enamel opacities and hypoplasia, oral counts of MS and LB, and dental caries. Bacterial counts were assessed using a commercial microbiological kit. Thirty-four MZ and 50 DZ twins (mean gestational age 35.0 ± 2.4 weeks, and birthweight 2.4 ± 0.6 kg) were examined. There were no statistically significant differences between MZ and DZ twins in the prevalence of MS, LB, and enamel hypoplasia. Concordance rates for MS and LB presence and prevalence of enamel defects within MZ and DZ twin pairs were not significantly different. There were more children with caries in DZ compared with MZ twins (18% vs 3%, P = 0.0029), most likely due to increased daily frequency of sugar consumption and less toothbrushing. Concordance data from MZ and DZ twins did not demonstrate any statistically significant difference in susceptibility for enamel defects and colonization of MS and LB. “
“Facial and dental appearance influences how individuals are perceived by others. This study aimed to determine whether young people make judgements about other young people with visible enamel opacities.