PubMedCrossRef 11 Starcevic A, Zucko

PubMedCrossRef 11. Starcevic A, Zucko selleck compound J, Simunkovic J, Long PF, Cullum J, Hranueli D: ClustScan: an integrated program package for the semi-automatic annotation of modular biosynthetic gene learn more clusters and in silico prediction of novel chemical structures. Nucleic Acids Res 2008, 36:6882–92.PubMedCrossRef 12. Li MH, Ung PM, Zajkowski J, Garneau-Tsodikova S, Sherman DH: Automated genome mining for natural products. BMC Bioinformatics 2009, 10:185.PubMedCrossRef 13. Medema MH, Blin K, Cimermancic P, de Jager V, Zakrzewski P, Fischbach MA, Weber T, Takano E, Breitling R: antiSMASH: rapid identification, annotation and analysis of secondary

metabolite biosynthesis gene clusters in bacterial and fungal genome sequences. Nucleic Acids Res 2011, 39:W339–46.PubMedCrossRef 14. Rawlings BJ: Biosynthesis of polyketides (other than actinomycete macrolides). Nat Prod Rep 1999, 16:425–84.PubMedCrossRef 15. Marchler-Bauer A, Panchenko

AR, Shoemaker BA, Thiessen PA, Geer LY, Bryant SH: CDD: a database of conserved domain alignments with links to domain three-dimensional structure. Nucleic Acid Res 2002, 30:281–3.PubMedCrossRef 16. Bateman A, Birney E, Cerruti L, Durbin R, Etwiller L, Eddy SR, Griffiths-Jones S, Howe KL, Marshall M, Sonnhammer EL: The Pfam protein families database. Nucleic Acid Res 2002, 30:276–280.PubMedCrossRef Selleck BIIB057 17. Altschul SF, Gish W, Miller W, Myers EW, Lipman DJ: Basic local alignment search tool. J Mol Biol 1990, 215:403–10.PubMed 18. Zawada RJ, Khosla C: Domain analysis of the molecular recognition features of aromatic polyketide Adenosine synthase subunits. J Biol Chem

1997, 272:16184–8.PubMedCrossRef 19. Liao L, Noble WS: Combining pairwise sequence similarity and support vector machines for detecting remote protein evolutionary and structural relationships. J Comput Biol 2003, 10:857–68.PubMedCrossRef 20. Eddy SR: Profile hidden Markov models. Bioinformatics 1998, 14:755–63.PubMedCrossRef 21. Chang CCL,   CJ: Training nu-support vector classifiers: theory and algorithms. Neural Comput 2001, 9:1443–1471. 22. Pearson WR, Lipman DJ: Improved tools for biological sequence comparison. Proc Natl Acad Sci U S A 1988, 85:2444–8.PubMedCrossRef 23. Zhao W, Zhong Y, Yuan H, Wang J, Zheng H, Wang Y, Cen X, Xu F, Bai J, Han X, Lu G, Zhu Y, Shao Z, Yan H, Li C, Peng N, Zhang Z, Zhang Y, Lin W, Fan Y, Qin Z, Hu Y, Zhu B, Wang S, Ding X, Zhao GP: Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism. Cell Res 2010, 20:1096–108.PubMedCrossRef 24.

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