The substrates were irradiated with 8 MeV electrons to a dose of 25 kGy prior to deposition. Ion scattering measurements indicated that the silver particulates are formed at a few NVP-BSK805 in vitro tens of nanometers beneath the PS surface for both unirradiated and irradiated substrates. The particulate structure seems to be a two-dimensional array rather than a three-dimensional distribution. The morphology of the particulate structure, the depth of maximum concentration of the particles as well as the width of the distribution seems to depend on the
deposition rate and substrate temperature. The electron irradiation of the PS substrate gives rise to the modification of the morphology of the particulate structure due to the induced polymer-metal interaction AZD8055 solubility dmso arising from the free radicals created by the irradiation. (C) 2011 American Institute of Physics. [doi: 10.1063/1.3626470]“
“Objective
To examine whether immunocytochemistry can distinguish pulmonary large cell neuroendocrine carcinoma (LCAEC) among non-small cell lung cancers (NSCLCs).
Study Design
Tumor touch imprint cytologic specimens of 109 lung cancers were studied. Immunocytochemistry was done using a total of 8 primary antibodies. chromogranin A, synaptophysin, neural cell adhesion molecule,
neuron specific enolase, CK34 beta E12, thyroid transcription factor-1, cytokeratin 18 and E-cadherin.
Results
If 2 or 3 antibodies of chromogranin A, synaptophysin and neural cell adhesion molecule were stained positive and CK340E12 was not stained, pulmonary LCNEC can be selected accurately among other NSCLCs with 100% sensitivity and
100% specificity.
Conclusion
This study reveals that immunocytochemistry can help distinguish LCAEC of the lung from other NSCLCs. (Acta Cytol 2009;53:36-40)”
“A Flurbiprofen (FP) cationic liposomes in situ gelling system (CLIGS) of thermosensitive polymers was proposed; we investigated its in vitro and in vivo properties, and its potential use in ocular drug delivery was evaluated. This system, optimized via center composite design, was conceived from a combination of polymer- and lipid-based delivery Sapanisertib mw systems. Therefore, the system could integrate the advantages of both cationic liposomes and in situ gels and further improve the poor stability of cationic liposomes. Cationic liposomes were characterized for their particle size, shape, entrapment efficiency, zeta potential, and photograph of transmission electron microscopy. The in vitro penetration capability and precorneal retention time of the FP CLIGS were evaluated by a vertical Franz-type cell method and gamma scintigaraphy, respectively. The FP CLIGS showed an improved stability during a 30-day storage period over than of FP cationic liposomes.